BioSHaRE Deliverables


WP 1   Coordination and Management

D1.8     Catalogue of standardized data within European biobanks - November 2015 (M60)


WP 2   Data repository and epidemiological/ clinical harmonization

D2.2     Validated phenotype systems - November 2013 (M36)

D2.3     DataSHaPER harmonization rules defined and integrated into phenotype system - May 2014 (M42)


WP 3   Epidemiology and Biostatistics for Biobank Harmonization

D3.1     ESPRESSO-forte Study Simulation Platform completed - November 2014 (M48)

D3.2     Working version of DataSHIELD completed - December 2013 (M37)

D3.3     Complete analysis and report results of two case studies in collaboration with WP9 - November 2014 (M48)

D3.5     Implementation of model(s) in DataSHIELD for use in BioSHaRE - November 2015 (M60)

D3.6     Manuscript on model(s) for harmonizing longitudinal data - November 2015 (M60)

D3.7     Report on the social and epistemic implications of the DataSHIELD methodology - November 2015 (M60)

D3.8     Report on Social and epistemic implications of biobank standardisation and harmonisation - November 2015 (M60)

            EnMESHD - Evaluation of tools and MEthods for Sharing Data - November 2015


WP4    Bioinformatics standardization/ harmonization for optimised information management 

D4.1     Full scope data exchange format

D4.2     Final version modular database system - November 2015 (M60)

D4.3     Validated researcher digital IDs for control of data access - November 2015 (M60)

D4.4     Object models for experiment and molecular data - December 2014


WP5    Biospecimen harmonization/standardization

D5.1     Evidence-based minimal standards for important samples types and measurement techniques

D5.2     SOPs for standardisation of sample collection, sample pre-treatment and sample analysis

D5.3     Temperature effects of preparing and thawing samples on different analyses techniques

D5.4     SOPs for shipment of samples and laboratory analyses of inflammatory markers from different biobanks - January 2015

D5.6     Scientific report on harmonization and standardization of prospective phenotypes for future research - November 2015 (M60)

D5.7     Scientific paper on GWA / GWI studies on obesity, healthy obesity and associated comorbidity - November 2015 (M60)

D5.8     Scientific paper on health outcome for Healthy Obese phenotypes - November 2015 (M60)

D5.9     Scientific paper on the use and utility of inflammatory markers in Healthy Obese individuals - November 2015 (M60)


WP6    Metabolomic and genetic risk factors for clustering of complex diseases

D6.1     Report of harmonized analyses and associated patterns

D6.2     Recommendations for utilization of omical data and/or identified patterns in disease prevention, diagnosis and treatment


WP7    Societal and environmental risk factors for complex diseases

D7.2     Georeferencing of individual cohort data

D7.3     Integrated EU GIS toolkit, part I, part II

D7.4     Working version of EnviroSHaPER completed

D7.5     Complex lifestyle and risk factor variables harmonized - November 2015 (M60)

D7.6     Scientific paper on the relation between the harmonized complex variables and risk factors and specific health outcomes - November 2015 (M60)

D7.7     Scientific report on harmonization of life habits/behaviors, physical and social environment, and socio-economic status variables - November 2015 (M60)


WP8    Strategic integration and coordination with major biobanking initiatives, partnerships and dissemination

D8.1     Horizon scanning plan for key activities in BioSHaRE-EU

D8.2     Scientific conference

D8.3     Consensus report on the distinction between standardization and harmonization

D8.4     Coordinate responses from projects

D8.5     Final plan for the use and dissemination of foreground - November 2015 (M60)

D8.6     Report on Awareness and Wider Societal Implications - November 2015 (M60)


WP9    Implementation & Roll-out

D9.1     Catalogue resources in P3G, BBMRI and large consortia

D9.2     Complete analysis and report results of two case studies in collaboration with WP3 - November 2014 (M48)


Ethical, legal and social issues

D2.4     Data sharing protocols

D2.5     Carry out a review of the requirements for the sharing of data

D3.4     Ethico-legal code of conduct for research

D5.5     ELSI standards for the use of biospecimen from multiple biobanks

D6.3     ELSI Standards for the use of genetic and metabolomic data 

D7.1     ELSI guidance on the specific issues associated with use of environmental risk and personal life-style data in and from different European, comprehensive biobanks

D9.3     ELSI tools for standardization and harmonisation to use data from different biobanks